Multi-scale hybrid and agent-based modeling of cell differentiation
نویسندگان
چکیده
In this work we propose a hybrid model of cell population dynamics, where cells are considered as discrete elements whose dynamics depending on the intracellular and extracellular regulation. The takes into account different types which include undifferentiated two differentiated cells. We use simulation algorithm based dynamical systems approach one hand, multi-agent other hand. Both approaches have been implemented using NetLogo Python. discuss choice between analyze coexistence lineages.
منابع مشابه
A framework for multi-Scale Agent- based biomedical modeling
Multi-scale modeling of complex biological systems remains a central challenge in the systems biology community. A method of dynamic knowledge representation known as agent-based modeling enables the study of higher level behavior emerging from discrete events performed by individual components. With the advancement of computer technology, agent-based modeling has emerged as an innovative techn...
متن کاملLarge-scale Agent-based Modeling and Simulation
This research presents a method to build large-scale agent-based modeling and simulation on PC for large-scale social systems with complex social networks. The novelty of this method is reflected in both designing of individual agent and organizing a group of agents for interactions on a large scale. As a case study, we constructed a large-scale artificial city Beijing, on which to test policie...
متن کاملLarge-Scale Multi-agent-Based Modeling and Simulation of Microblogging-Based Online Social Network
Online Social Networks (OSN) are self-organized systems with emergent behavior from the individual interactions. Microblogging services in OSN, like Twitter and Facebook, became extremely popular and are being used to target marketing campaigns. Key known issues on this targeting is to be able to predict human behavior like posting, forwarding or replying a message with regard to topics and sen...
متن کاملHybrid multi-agent systems: modeling, specification and verification
Specifying behaviors of multi-agent systems (MASs) is a demanding task, especially when applied in safety-critical systems. In the latter systems, the specification of behaviors has to be carried out carefully in order to avoid side effects that might cause unwanted or even disastrous behaviors. Thus, formal methods based on mathematical models of the system under design are helpful. They not o...
متن کاملMulti-Agent Systems: Modeling and Verification Using Hybrid Automata
Hybrid automata are used as standard means for the specification and analysis of dynamical systems. Several researches have approached them to formally specify reactive Multi-agent systems situated in a physical environment, where the agents react continuously to their environment. The specified systems, in turn, are formally checked with the help of existing hybrid automata verification tools....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Mathematical modeling and computing
سال: 2023
ISSN: ['2312-9794', '2415-3788']
DOI: https://doi.org/10.23939/mmc2023.03.617